22 And the rib, which the LORD God had taken from man, made he a woman, and brought her unto the man.
23 And Adam said, This is now bone of my bones, and flesh of my flesh: she shall be called Woman, because she was taken out of Man.
24 Therefore shall a man leave his father and his mother, and shall cleave unto his wife: and they shall be one flesh.
This does not mean that a man should forget about his parents, never have anything to do with them again and go to the woman's family and take up a new life. If that were so, Jesus would not be preparing a place for us at His Father's House.
It simply means that a man and his wife become "one". Where ever the man goes, the woman goes WITH him. Whatever the woman goes through, the man goes through it WITH her. Everything he chooses to experience, he must consider how it will effect his wife, and vice versa. It is a matter of INCLUSION, not a matter of choice.